Full-Dose PET Image Estimation from Low-Dose PET Image Using Deep Learning: a Pilot Study

200x Low-dose PET Reconstruction using Deep Learning

Positron emission tomography (PET) is widely used in various clinical applications, including cancer diagnosis, heart disease and neuro disorders. The use of radioactive tracer in PET imaging raises concerns due to the risk of radiation exposure. To minimize this potential risk in PET imaging, efforts have been made to reduce the amount of radiotracer usage. However, lowing dose results in low ...

PET/CT in lymphoma: prospective study of enhanced full-dose PET/CT versus unenhanced low-dose PET/CT.

UNLABELLED PET/CT combines functional and morphologic data and increases diagnostic accuracy in a variety of malignancies. This study prospectively compares the agreement between contrast-enhanced full-dose PET/CT and unenhanced low-dose PET/CT in lesion detection and initial staging of Hodgkin's disease and non-Hodgkin's lymphoma. METHODS Forty-seven biopsy-proven lymphoma patients underwent...

Estimation of fetal absorbed dose from low-dose attenuation-correction CT in PET / CT imaging by using the Body Builder Phantom

One of the methods of studying the physiology and metabolism of important tissues such as the heart, brain and cancer tumors is the use of PET/CT System. A small number of patients are pregnant women who undergo a PET/CT scan due to lack of knowledge about pregnancy or due to dire clinical need. The final dose received by the fetus is based on three factors: the absorbed dose of the fetal tissu...

Low Dose PET Image Reconstruction with Total Variation Using Alternating Direction Method

In this paper, a total variation (TV) minimization strategy is proposed to overcome the problem of sparse spatial resolution and large amounts of noise in low dose positron emission tomography (PET) imaging reconstruction. Two types of objective function were established based on two statistical models of measured PET data, least-square (LS) TV for the Gaussian distribution and Poisson-TV for t...

A Multi-level Canonical Correlation Analysis Scheme for Standard-Dose PET Image Estimation